Arizona Cardinals vs San Francisco 49ers

ARIZONA CARDINALS VS SAN FRANCISCO 49ERS

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The Cardinals face off against the 49ers for week 1 in this matchup. For the Cardinals, Kyler Murray will lead the way at quarterback with their new addition of DeAndre Hopkins at wide reciever. Kenyan Drake will tallie most of the carries from the backfield as we see this Cardinals offense make little strides each year to get better. On Defense, they will likely struggle as they are coming off a terrible season last year.

For the 49ers, Jimmy Garoppolo will lead the way at quarterback. The 49ers wide receivers are pretty banged up so I expect them to rely heavily on George Kittle and Jordan Reed at tight end to get the job Done. In the backfield, the 49ers will rotate between Raheem Mostert and Tevin Coleman, while using Jerick McKinnon and Jeff Wilson Jr sparingly. On defense, the 49ers are still top tier and should be effective against the Cardinals aside from trying to stop DeAndre Hopkins.

I like the 49ers to cover the spread here. Even though they are lacking in wide reciever, George Kittle is still one of the best tight ends in the league, & if the double him all game I can see Jordan Reed getting in on the action to help propel them to a victory.

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